Bringing the future into focus

Dr. Thomas Theelen

Dr. Theelen is specialized in retinal imaging, medical retina and glaucoma. He has developed novel minimal invasive vitrectomy techniques and pioneered the use of non-penetrating glaucoma surgery (canaloplasty) in the Netherlands. His current research is focused on the development of novel functional imaging techniques of the retina.


  •  Medical studies and doctorate (summa cum laude) in Aachen
  •  Residency at University Eye Clinic Magdeburg and Mülheim a/d Ruhr
  •  Since 2003: associate professor at the Radboud University Nijmegen Medical Centre
  • PhD in Medicine (2011, Radboud University, Nijmegen): "Scanning laser Imaging of the Retina - Basic Concepts and Clinical Applications"
  • Head research deparmtent "Functional retina imaging", RadboudUMC Nijmegen


  • Functional Retinal imaging (fundus autofluorescence, infrared imaging, optical coherence tomography)
  • Digital image analysis in ophthalmology


  •  Patient evaluation
  •  Biomarker identification and imaging

Selected publications

  • van Grinsven MJ, Lechanteur YT, van de Ven JP, van Ginneken B, Hoyng CB, Theelen T, Sánchez CI. Automatic drusen quantification and risk assessment of age-related macular degeneration on color fundus images. Invest Ophthalmol Vis Sci 2013; 54(4):3019-3027. Pubmed
  • Theelen T, Berendschot TT, Klevering BJ, Fuijkschot J, Hoyng CB, Willemsen MA. Multimodal imaging of the macula in hereditary and acquired lack of macular pigment. Acta Ophthalmol 2014; 92(2):138-142. Pubmed
  • van de Ven JP, Boon CJ, Smailhodzic D, Lechanteur YT, den Hollander AI, Hoyng CB, Theelen T. Short-term changes of basal laminar drusen on spectral-domain optical coherence tomography. Am J Ophthalmol 2012; 154(3):560-567. Pubmed
  • Smailhodzic D, Fleckenstein M, Theelen T, Boon CJ, van Huet RA, van de Ven JP, den Hollander AI, Schmitz-Valckenberg S, Hoyng CB, Weber BH, Holz FG, Klevering BJ. Central areolar choroidal dystrophy (CACD) and age-related macular degeneration (AMD): differentiating characteristics in multimodal imaging. Invest Ophthalmol Vis Sci 2011; 52(12):8908-8918. Pubmed
  • van der Veen RL, Fuijkschot J, Willemsen MA, Cruysberg JR, Berendschot TT, Theelen T. Patients with Sjögren-Larsson syndrome lack macular pigment. Ophthalmology 2010; 117(5):966-971. Pubmed
  • Theelen T, Berendschot TT, Hoyng CB, Boon CJ, Klevering BJ. Near-infrared reflectance imaging of neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2009;247(12):1625-1633. Pubmed
  • Boon CJ, Klevering JB, Keunen JE, Hoyng CB, Theelen T. Fundus autofluorescence imaging of retinal dystrophies. Vision Res 2008; 48(26):2569-2577. Pubmed
  •  Theelen T, Berendschot TT, Boon CJ, Hoyng CB, Klevering BJ. Analysis of visual pigment by fundus autofluorescence. Exp Eye Res. 2008;86(2):296-304. Pubmed
  • Theelen T, Boon CJ, Klevering BJ, Hoyng CB. [Fundus autofluorescence in patients with inherited retinal diseases : patterns of fluorescence at two different wavelengths].  Ophthalmologe 2008;105(11):1013-1022. Pubmed
  • Fuijkschot J, Cruysberg JR, Willemsen MA, Keunen JE, Theelen T. Subclinical changes in the juvenile crystalline macular dystrophy in Sjögren-Larsson syndrome detected by optical coherence tomography. Ophthalmology 2008;115(5):870-875. Pubmed
  • Boon CJ, Klevering BJ, den Hollander AI, Zonneveld MN, Theelen T, Cremers FP, Hoyng CB. Clinical and genetic heterogeneity in multifocal vitelliform dystrophy. Arch Ophthalmol 2007;125(8):1100-1106. Pubmed
  • Boon CJ, van Schooneveld MJ, den Hollander AI, van Lith-Verhoeven JJ, Zonneveld-Vrieling MN, Theelen T, Cremers FP, Hoyng CB, Klevering BJ. Mutations in the peripherin/RDS gene are an important cause of multifocal pattern dystrophy simulating STGD1/fundus flavimaculatus. Br J Ophthalmol 2007;91(11):1504-1511. Pubmed